This is a normal issue for people that have very strong security measures

Steps to prevent this are:
1. Close icomancer
2. Delte the file manually
3. Either run icomancer as administrator or mark it as trusted in your security program so this don't happend again.

By the way, I've just added an exception handler to show this message instead of crashing.

System.UnauthorizedAccessException: Access to the path 'C:\ProgramData\LAVA SoftWorks\icomancer\collections_cache' is denied.
at System.IO.__Error.WinIOError(Int32 errorCode, String maybeFullPath)
at System.IO.FileInfo.Delete()
at Icomancer.frmLauncher.btnConnectDisconnect_Click(Object sender, EventArgs e) in H:\Icomancer\Icomancer\frmLauncher.vb:line 195
at System.Windows.Forms.Control.OnClick(EventArgs e)
at System.Windows.Forms.Button.OnClick(EventArgs e)
at System.Windows.Forms.Button.OnMouseUp(MouseEventArgs mevent)
at System.Windows.Forms.Control.WmMouseUp(Message& m, MouseButtons button, Int32 clicks)
at System.Windows.Forms.Control.WndProc(Message& m)
at System.Windows.Forms.ButtonBase.WndProc(Message& m)
at System.Windows.Forms.Button.WndProc(Message& m)
at System.Windows.Forms.Control.ControlNativeWindow.OnMessage(Message& m)
at System.Windows.Forms.Control.ControlNativeWindow.WndProc(Message& m)
at System.Windows.Forms.NativeWindow.Callback(IntPtr hWnd, Int32 msg, IntPtr wparam, IntPtr lparam)

Please take a screen shot of this and send it to icomancer_support@lavasoftworks.com so we can figure out how to fix it.