Try running it as administrator. If the problem persists, it is possible that you have an inavild temp folder specified in your Windows user profile. In such case, let me know and I can give you further instructions to fix it :)

An application unhandled exception has raised:

System.IO.DirectoryNotFoundException: Could not find a part of the path 'C:\Users\clee\AppData\Local\Temp\'.
at System.IO.__Error.WinIOError(Int32 errorCode, String maybeFullPath)
at System.IO.File.InternalCopy(String sourceFileName, String destFileName, Boolean overwrite, Boolean checkHost)
at System.IO.FileInfo.CopyTo(String destFileName)
at Icomancer.Functions.UploadIcon(String fileName, XElement xmlData, TransferrableFlags TransferrableFlag, Boolean ShowGUI) in H:\Icomancer\Icomancer\Functions.vb:line 2258
at Icomancer.frmCrafter.btnSaveAll_Click(Object sender, EventArgs e) in H:\Icomancer\Icomancer\frmCrafter.vb:line 1230
at System.Windows.Forms.Control.OnClick(EventArgs e)
at System.Windows.Forms.Button.OnClick(EventArgs e)
at System.Windows.Forms.Button.OnMouseUp(MouseEventArgs mevent)
at System.Windows.Forms.Control.WmMouseUp(Message& m, MouseButtons button, Int32 clicks)
at System.Windows.Forms.Control.WndProc(Message& m)
at System.Windows.Forms.ButtonBase.WndProc(Message& m)
at System.Windows.Forms.Button.WndProc(Message& m)
at System.Windows.Forms.Control.ControlNativeWindow.OnMessage(Message& m)
at System.Windows.Forms.Control.ControlNativeWindow.WndProc(Message& m)
at System.Windows.Forms.NativeWindow.Callback(IntPtr hWnd, Int32 msg, IntPtr wparam, IntPtr lparam)

Please take a screen shot of this and send it to icomancer_support@lavasoftworks.com so we can figure out how to fix it.